Engineering biodegradable and multifunctional peptide-based polymers for gene delivery
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چکیده
منابع مشابه
Engineering biodegradable and multifunctional peptide-based polymers for gene delivery
The complex nature of in vivo gene transfer establishes the need for multifunctional delivery vectors capable of meeting these challenges. An additional consideration for clinical translation of synthetic delivery formulations is reproducibility and scale-up of materials. In this review, we summarize our work over the last five years in developing a modular approach for synthesizing peptide-bas...
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Poly[(organo)phosphazenes] are a unique class of extremely versatile polymers with a range of applications including tissue engineering and drug delivery, as hydrogels, shape memory polymers and as stimuli responsive materials. This review aims to divulge the basic principles of designing polyphosphazenes for drug and gene delivery and portray the huge potential of these extremely versatile mat...
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ژورنال
عنوان ژورنال: Journal of Biological Engineering
سال: 2013
ISSN: 1754-1611
DOI: 10.1186/1754-1611-7-25